| First Author | Kalueff AV | Year | 2006 |
| Journal | Behav Processes | Volume | 72 |
| Issue | 1 | Pages | 104-12 |
| PubMed ID | 16442749 | Mgi Jnum | J:112776 |
| Mgi Id | MGI:3663547 | Doi | 10.1016/j.beproc.2005.12.011 |
| Citation | Kalueff AV, et al. (2006) Temporal stability of novelty exploration in mice exposed to different open field tests. Behav Processes 72(1):104-12 |
| abstractText | We investigated behavioural activity and temporal distribution (patterning) of mouse exploration in different open field (OF) arenas. Mice of 129S1 (S1) strain were subjected in parallel to three different OF arenas (Experiment 1), two different OF arenas in two trials (Experiment 2) or two trials of the same OF test (Experiment 3). Overall, mice demonstrated a high degree of similarity in the temporal profile of novelty-induced horizontal and vertical exploration (regardless of the size, colour and shape of the OF), which remained stable in subsequent OF exposures. In Experiments 4 and 5, we tested F1 hybrid mice (BALB/c-S1; NMRI-S1), and Vitamin D receptor knockout mice (generated on S1 genetic background), again showing strikingly similar temporal patterns of their OF exploration, despite marked behavioural strain differences in anxiety and activity. These results suggest that mice are characterised by stability of temporal organization of their exploration in different OF novelty situations. |
