Primary Identifier | MGI:1861103 | Allele Type | Transgenic |
Gene | Hfm | Inheritance Mode | Dominant |
Strain of Origin | SWV-Mbp<shi> | Is Recombinase | false |
Is Wild Type | false |
description | This mutation was generated by by pronuclear injection of a transgene into SWV-Mbpshi fertilized oocytes. Approximately 50-100 copies initially inserted into this locus, but the copy number decreased to 1 or a few during the course of breeding. This decrease of copy number had no effect on the phenotype. Some mice were mated to a B6C female to expand to an F3 generation. |
molecularNote | A 23 Kb deletion on chromosome 10 occurred at the integration site of a transgene that expressed myelin basic protein. |