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Allele : Hfm hemifacial microsomia-associated locus

Primary Identifier  MGI:1861103 Allele Type  Transgenic
Gene  Hfm Inheritance Mode  Dominant
Strain of Origin  SWV-Mbp<shi> Is Recombinase  false
Is Wild Type  false
description  This mutation was generated by by pronuclear injection of a transgene into SWV-Mbpshi fertilized oocytes. Approximately 50-100 copies initially inserted into this locus, but the copy number decreased to 1 or a few during the course of breeding. This decrease of copy number had no effect on the phenotype. Some mice were mated to a B6C female to expand to an F3 generation.
molecularNote  A 23 Kb deletion on chromosome 10 occurred at the integration site of a transgene that expressed myelin basic protein.
  • mutations:
  • Deletion,
  • Insertion
  • synonyms:
  • 643-7,
  • Tg(MBP)643Mok,
  • 643-7,
  • Tg(MBP)643Mok,
  • microtia,
  • microtia
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1 Feature

Trail: Allele

Genome

0 Expresses

1 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele