| First Author | Juriloff DM | Year | 1991 |
| Journal | J Hered | Volume | 82 |
| Issue | 5 | Pages | 402-5 |
| PubMed ID | 1940283 | Mgi Jnum | J:1621 |
| Mgi Id | MGI:50148 | Doi | 10.1093/oxfordjournals.jhered.a111111 |
| Citation | Juriloff DM, et al. (1991) Mapping the mouse craniofacial mutation first arch (Far) to chromosome 2. J Hered 82(5):402-5 |
| abstractText | First arch (Far) is a semidominant mutation that causes severe craniofacial defects in mice. Here we report the results of linkage studies with the chromosome 2 markers nonagouti, pallid, and Ulnaless. Far is loosely linked to nonagouti (24-37 cM), more closely linked to pallid (13-28 cM), and closely linked to Ulnaless (2.3 +/- 1.5 cM). The embryological defect in Far mutants is confined to one segmentally-derived region of the head, the anterior first branchial arch. It may therefore be significant that, in mapping near Ulnaless, Far also maps in the vicinity of the Hox-4 gene cluster. |
