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Publication : In vivo and in vitro studies on the early embryonic lethal tail-short (Ts) in the mouse.

First Author  Paterson HF Year  1980
Journal  J Exp Zool Volume  211
Issue  2 Pages  247-56
PubMed ID  7373273 Mgi Jnum  J:6315
Mgi Id  MGI:54791 Doi  10.1002/jez.1402110214
Citation  Paterson HF (1980) In vivo and in vitro studies on the early embryonic lethal tail-short (Ts) in the mouse. J Exp Zool 211(2):247-56
abstractText  An histological study reveals that embryos homozygous for the mutation tail-short (Ts) become abnormal as morulae, although a small amount of cell division may continue to take place during the following day. Homozygotes can be identified at 3 1/2 days post coitum (p.c.) by several criteria including low cell number, absence of cavitation, and weak cytoplasmic staining with haematoxylin. A similar pattern of developmental arrest is exhibited during culture, although an initial degree of cavitation occurs more frequently.
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