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Allele : War warfarin resistance

Primary Identifier  MGI:1861144 Allele Type  Chemically induced (other)
Gene  War Inheritance Mode  Semidominant
Strain of Origin  PBI Is Recombinase  false
Is Wild Type  false
description  Found in a wild population in the Plant Breeding Institute, Cambridge. It was discovered because it occurred in this population on the same chromosome as a closely linked color mutation, extreme dilution (Tyrc-e), whose frequency was noted to be increasing. Wild-type mice of both sexes were fully susceptible when tested at 4 months of age. Both War/War and War/+ females were fully resistant when tested under the same conditions. Less than 100 per cent of similarly tested War/War males were resistant, and the proportion of resistant War/+ males was intermediate between that and 0 per cent. Modifying genetic factors affected the degree of resistance in males but not in females. A similar mutation for warfarin resistance occurs in the rat and occupies an analogous position linked to the p and Tyr loci in that species (J:5635).
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele