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Allele : Crygs<Opj> crystallin, gamma S; opacity due to poor secondary fiber cell junctions

Primary Identifier  MGI:1861635 Allele Type  Chemically induced (ENU)
Gene  Crygs Inheritance Mode  Semidominant
Strain of Origin  (101 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A single base pair mutation (T to C) in exon 2 replaces Phe with Ser at amino acid position 9 of the protein. The mutant protein shows a concentration dependent decrease in solubility and a loss of secondary structure at near-physiological temperatures.
  • mutations:
  • Single point mutation
  • synonyms:
  • ENU-410,
  • ENU-410
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele