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Allele : Hprt1<tm1Detl> hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Peter J Detloff

Primary Identifier  MGI:1861939 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Hprt1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A construct was created that introduced a long CAG repeat (n=146 units) into an Xho1 site in exon 3 of a genomic fragment of the locus. An additional 4.9kb genomic fragment, which included exon 4 of the gene, was added to this repeat-containing construct. Appropriately targeted clones had sequences containing the 146-unit CAG repeat, encoding a stretch of 146 glutamines, in place of wild-type exon 3.
  • mutations:
  • Insertion
  • synonyms:
  • hprt<(CAG)146>,
  • JO1,
  • JO1,
  • hprt<(CAG)146>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele