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Publication : The fate of Ds homozygotes

First Author  Guenet JL Year  1976
Journal  Mouse News Lett Volume  54
Pages  51 Mgi Jnum  J:15079
Mgi Id  MGI:63218 Citation  Guenet JL (1976) The fate of Ds homozygotes. Mouse News Lett 54:51
abstractText  Full text of MNL contribution: Research News: The fate of Ds homozygotes: In order to study the fate of the Ds/Ds homozygotes we have intercrossed Ds +/+ hr animals. Out of 84 progeny analysed 18 had the hr phenotype (hr/hr). This is significantly different from the 1/3 proportion expected if it was true that Ds and hr are linked and Ds/Ds lethal. To try to further understand this, 41 progeny were tested amongst which 27 were .../+ hr and 14 were non .../+ hr. All the 20 males amongst these 41 progeny were also tested and all were shown to be carrying the Ds mutation. These results seem to show that Ds is probably linked to hr but that at least certain homozygotes are able to reach adulthood in our experimental conditions.
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