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Allele : Aga<tm1Vk> aspartylglucosaminidase; targeted mutation 1, Vesa Kaartinen

Primary Identifier  MGI:1861793 Allele Type  Targeted
Attribute String  Null/knockout Gene  Aga
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into the coding sequences in exon 3. Northern blot analysis and RT-PCR demonstrated that no detectable transcript is produced from this allele. Enzyme activity assays on liver and brain extracts of homozygous mice confirmed that no functional protein is made from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • Aga-,
  • AGU,
  • Aga-,
  • AGU
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele