|  Help  |  About  |  Contact Us

Allele : Psap<tm1Suz> prosaposin; targeted mutation 1, Kunihiko Suzuki

Primary Identifier  MGI:1888378 Allele Type  Targeted
Attribute String  Null/knockout Gene  Psap
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was disrupted by the insertion of a neomycin selection cassette. Northern blot analysis of tissues obtained from homozygous mutant mice showed an absence Saposin precursor mRNA. Homozygous mice lack all four types of sphingolipid activator proteins (A, B, C, and D).
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PS<->,
  • prosaposin<->,
  • prosaposin<->,
  • SAP-,
  • SAP-,
  • PS<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

33 Publication categories

Trail: Allele