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Allele : Stat6<tm1Gru> signal transducer and activator of transcription 6; targeted mutation 1, Michael J Grusby

Primary Identifier  MGI:1888385 Allele Type  Targeted
Attribute String  Null/knockout Gene  Stat6
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The region encoding the SH2 domain, which is essential for dimerization, was replaced by the insertion of a neomycin selection cassette. Immunoblot analysis of lysates from the spleens and thymi of homozygous mutant mice showed an absence of encoded protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • S6KO,
  • S6KO,
  • Stat6<->,
  • Stat6<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

9 Carried By

Trail: Allele

0 Driven By

392 Publication categories

Trail: Allele