| Primary Identifier | MGI:1927607 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Myf6 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| description | Homozygotes show absence of Myf5 expression and resemble most of the phenotypes seen in Myf5 null mice (J:24360). Analysis has shown that most likely, Myf6 regulates Myf5 expression by a cis-acting mechanism and the skeletal abnormalities result from the absence of Myf5 rather than Myf6 (J:31636, J:42453). |
| molecularNote | A neomycin selection cassette was inserted into exon 1 of the gene, removing nucleotides -5 to +207. This disruption was shown to eliminate Myf5 expression as well. |
