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Allele : Nrg1<tm1Lwr> neuregulin 1; targeted mutation 1, Lorna W Role

Primary Identifier  MGI:1928831 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nrg1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  The cysteine-rich domain (CRD) in the alternatively spliced N-terminus was disrupted by the creation of a nonsense mutation and an Xba1 site in the exon encoding the CRD. A loxP site flanked neomycin resistance gene cassette was inserted into the intron following the CRD-encoding exon.
  • mutations:
  • Insertion
  • synonyms:
  • CRD-NRG-1<->,
  • Nrg1<tm1.1Lwr>,
  • Type III Nrg1<->,
  • Type III Nrg1<->,
  • Nrg1<tm1.1Lwr>,
  • Nrg1<Lwrtm1>,
  • CRD-NRG-1<->,
  • Nrg1<Lwrtm1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

31 Publication categories

Trail: Allele