Primary Identifier | MGI:1931883 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Xpc |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An hprt expression cassette replaced four exons and introduced a frameshift and two stop codons downstream of the mutation. RT-PCR studies of embryonic fibroblast cells detected an aberrant short Xpc transcript in homozygous mutant mice. |