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Allele : Cr2<tm1Hmo> complement receptor 2; targeted mutation 1, Hector Molina
Primary Identifier  MGI:1932568 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cr2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin resistance cassette replaced part of the first and all of the second exon encoding short consensus repeat (SCR) 14. Flow cytometry of spleen cells using three different rat antimouse CR2 monoclonal antibodies showed that homozygous mutant mice were deficient in the expression of the receptors.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CR1/2-,
  • Cr2-,
  • CR1/2-,
  • CR1/CR2-,
  • Cr,
  • Cr2-,
  • CD21-KO,
  • CD21-KO,
  • Cr,
  • CR1/CR2-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

48 Publication categories

Trail: Allele




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