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Allele : Dgat1<tm1Far> diacylglycerol O-acyltransferase 1; targeted mutation 1, Bob Farese

Primary Identifier  MGI:1934012 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dgat1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing sequences encoding the carboxy-terminus of the protein was replaced by a neomycin cassette. Northern blot analysis did not detect a full length transcript produced from this allele in homozygous mice. Tissue DGAT activity was absent ot severely reduced in homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

36 Publication categories

Trail: Allele