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Allele : Naglu<tm1Efn> alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB); targeted mutation 1, Elizabeth F Neufeld

Primary Identifier  MGI:1934018 Allele Type  Targeted
Attribute String  Null/knockout Gene  Naglu
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 of this gene, a region known to harbor several Sanfilippo B mutations, was disrupted by the insertion of a neomycin resistance gene via homologous recombination. Protein from homozygous mutant animals was negative for enzyme activity.
  • mutations:
  • Insertion
  • synonyms:
  • MPS IIIB,
  • Naglu-,
  • MPS IIIB,
  • Naglu-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

44 Publication categories

Trail: Allele