Primary Identifier | MGI:2135257 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Traf3 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neomycin resistance cassette replaced the first two exons. Western blot analysis using a polyclonal antibody against the C-terminal portion did not detect protein in three tissues of homozygous mutant mice. Northern blot analysis using a cDNA fragment that encodes the C-terminus did not detect mRNA in brain of homozygous mutant mice. |