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Allele : Fgfr3<tm1Cxd> fibroblast growth factor receptor 3; targeted mutation 1, Chu-Xia Deng

Primary Identifier  MGI:2135666 Allele Type  Targeted
Gene  Fgfr3 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Knock-in construct in which a portion of a cDNA corresponding to exons 5-19 followed by a polyadenylation signal was inserted into the endogenous locus. This allele carried a point mutation in codon 644 that altered the corresponding amino acid from lysine to glutamine. A loxP flanked neomycin cassette also inserted downstream of the inseted cDNA was removed via Cre mediated recombination in the final allele.
  • mutations:
  • Insertion
  • synonyms:
  • pFgfr3-TD,
  • pFgfr3-TD
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele