| Primary Identifier | MGI:1930939 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Psen2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Replacement of four codons in exon 5, corresponding to an RCYK motif in the second transmembrane domain, with a neomycin cassette. Brain extracts from homologous mutant mice showed no detectable Psen2 on Western blots using antibodies directed against the hydrophilic loop and the amino terminus of the protein. |
