Primary Identifier | MGI:1931861 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ncoa3 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced sequences encoding the CREB-binding protein (CBP) binding domain and much of the nuclear receptor interaction domain. Immunoblot analysis of kidney extract did not detect NCOA3 in homozygous mutant animals. |