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Allele : Runx1<tm1Sata> runt related transcription factor 1; targeted mutation 1, Masanobu Satake
Primary Identifier  MGI:1934197 Allele Type  Targeted
Attribute String  Null/knockout Gene  Runx1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4 was replaced by a PGK-neo cassette. The deleted region encoded the central portion of the conserved DNA-binding domain. Transcript was undetectable by RT-PCR analysis of extracts from the yolk sacs, livers, and aorta-mesonephros regions of homozygous mutant embryos.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Runx1<->,
  • Runx1<->,
  • AML1(-),
  • AML1(-)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

22 Publication categories

Trail: Allele




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