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Publication : The genetics of tasting in mice. VI. Saccharin, acesulfame, dulcin and sucrose.

First Author  Lush IE Year  1989
Journal  Genet Res Volume  53
Issue  2 Pages  95-9
PubMed ID  2744455 Mgi Jnum  J:9874
Mgi Id  MGI:58331 Doi  10.1017/s0016672300027968
Citation  Lush IE (1989) The genetics of tasting in mice. VI. Saccharin, acesulfame, dulcin and sucrose. Genet Res 53(2):95-9
abstractText  Twenty-six strains of mice were tested for their reaction to four different sweet substances; saccharin, acesulfame, dulcin and sucrose. There was considerable strain variation in the degree to which they found the sweet substances preferable to water. The variation in preference for any one sweet substance is very highly correlated with the variation in preference for the other sweet substances. This is interpreted to mean that there is only one sweetness receptor, although an alternative explanation in terms of variation in psychological motivation is not discounted. The difference between C57BL/6Ty and DBA/2Ty is largely due to a single gene, Sac.
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