Primary Identifier | MGI:2136844 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Gdnf |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A lacZ gene was inserted in-frame into the first coding exon. A neomycin resistance cassette was also inserted following the lacZ gene. This allele expresses a fusion protein consisting of the first 8 amino acids of GDNF fused to beta-galactosidase. |