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Allele : Utrn<tm1Jrs> utrophin; targeted mutation 1, Joshua R Sanes

Primary Identifier  MGI:2148539 Allele Type  Targeted
Attribute String  Null/knockout Gene  Utrn
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 2.7 kb of sequence including 52 bp of the exon that encodes the beginning of the C-terminal cysteine rich region. RT-PCR analysis demonstrated that a mutant transcript carrying the deletion was made in homozygous and heterozygous mice. Western blot analysis on extracts of muscle or lung tissue derived from homozygous mice confirmed that no detectable protein was expressed from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • utrn-,
  • uko,
  • uko,
  • utrn-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

62 Publication categories

Trail: Allele