| Primary Identifier | MGI:1934632 | Allele Type | Chemically induced (ENU) |
| Gene | Pax6 | Inheritance Mode | Not Specified |
| Strain of Origin | (C3H/HeN x BALB/cAnN)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | The phenotype in the Pax6Leca allelic series (Leca 1-4) produced a range of similar but variable eye phenotypes, with slightly smaller eyes and occasional adhensions between the lens and cornea.
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| molecularNote | The mutation underlying the phenotype in Leca3 mice was identified as a C to A substitution at nucleotide position 1266 of the Pax6 gene. The mutation occurs in exon 12 and introduces the Tyr369STOP change in the PST domain of the protein. |
