First Author | Beiting DP | Year | 2006 |
Journal | Infect Immun | Volume | 74 |
Issue | 3 | Pages | 1941-3 |
PubMed ID | 16495570 | Mgi Jnum | J:107378 |
Mgi Id | MGI:3621065 | Doi | 10.1128/IAI.74.3.1941-1943.2006 |
Citation | Beiting DP, et al. (2006) Synthesis of syndecan-1 by skeletal muscle cells is an early response to infection with Trichinella spiralis but is not essential for nurse cell development. Infect Immun 74(3):1941-3 |
abstractText | Trichinella spiralis creates a unique intracellular habitat in striated muscle. We report that a proteoglycan, syndecan-1, is induced early in infection yet is not essential for habitat development and exerts a modest influence on the immune response. This report is the first to address the requirement for a specific muscle protein in trichinellosis by using mice deficient in the relevant gene. |