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Allele : Slc12a2<tm1Dlp> solute carrier family 12, member 2; targeted mutation 1, Eric Delpire

Primary Identifier  MGI:1935225 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Slc12a2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Replacement of exon 9 with a beta-galactosidase/neomycin cassette. Inactivation of the protein transporter activity was demonstrated by measuring bumetanide-sensitive 86-Rb uptake in isolated erythrocytes. No iostopic uptake was seen in erythrocytes derived from homozygous mutant embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • NKCC1<->,
  • NKCC1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories

Trail: Allele