Primary Identifier | MGI:2135535 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, No functional change | Gene | Pdgfrb |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cDNA encoding PDGFbetaR was targeted into the Pdgfrb locus. This allele serves as a control for Pdgfrbtm5Sor. The cDNA was inserted in frame into a Sma1 site in the second coding exon. Western blot analysis indicated that expression of the targeted Pdgfr locus was disrupted and the introduced receptor was expressed. |