| Primary Identifier | MGI:2136289 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Abcb11 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The N-terminal ATP-binding domain, corresponding to amino acids 454-478, was deleted and replaced with a neo cassette. The construct introduced three missense mutations and a premature stop codon at position 454. Western analysis showed no detectable protein in homozygous mice. |
