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Allele : Gja8<tm1Scr> gap junction protein, alpha 8; targeted mutation 1, The Scripps Institute

Primary Identifier  MGI:2137525 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gja8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ gene, followed by a neomycin selection cassette, was inserted in-frame after the sixth codon. Western blot analysis demonstrated that no GJA8 protein is detectable in lens homogenates derived from homozygous mice. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • alpha8(-),
  • Gja8<m1>,
  • alpha8(-),
  • Gja8<m1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele