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Allele : Pik3r1<tm1Tka> phosphoinositide-3-kinase regulatory subunit 1; targeted mutation 1, Takashi Kadowaki

Primary Identifier  MGI:2149414 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pik3r1
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette replaced the first exon, exon 1A, of the gene. Functional analysis showed that deletion of this exon, which contains the initiation codon, abolished expression of the p85a variant, while not disrupting expression of the p50a or p55a splicing variants.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • p85alpha-,
  • PI3K p85alpha<->,
  • Pi3kr1-,
  • p85alpha-,
  • PI3K p85alpha<->,
  • Pi3kr1-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

52 Publication categories

Trail: Allele