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Allele : Gnaq<tm1Soff> guanine nucleotide binding protein, alpha q polypeptide; targeted mutation 1, Stefan Offermanns
Primary Identifier  MGI:2151661 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gnaq
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced 2.3 kb of sequence containing an exon that encodes amino acids 246-297 of the protein. Western blot analysis of whole brain and of cerebellar membrane fractions did not detect any protein produced from this allele in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Galphaq-,
  • Galphaq-,
  • Gnaq<->,
  • Gnaq<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

51 Publication categories





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