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Allele : Esr2<tm1Unc> estrogen receptor 2 (beta); targeted mutation 1, University of North Carolina
Primary Identifier  MGI:2152217 Allele Type  Targeted
Attribute String  Null/knockout Gene  Esr2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  ES cell line = BK4, which is derived from a subclone of E14TG2a.
molecularNote  A neomycin resistance cassette was inserted into exon 3 of the gene, introducing a stop codon and resulting in premature termination of translation of the Esr2 mRNA. Immunocytochemistry of ovary from homozygous mutant females showed no detectable Esr2 protein.
  • mutations:
  • Insertion
  • synonyms:
  • Erb-,
  • BERKO,
  • ERbeta-,
  • betaERKO,
  • ERbeta-,
  • BERKOChapel Hill,
  • beta-ERKO,
  • ERbetaKO,
  • beta-ERKO,
  • Erb-,
  • ERbetaKO,
  • BERKO,
  • BERKOChapel Hill,
  • betaERKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

202 Publication categories

Trail: Allele




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