| First Author | Caldarone B | Year | 1997 |
| Journal | Nat Genet | Volume | 17 |
| Issue | 3 | Pages | 335-7 |
| PubMed ID | 9354801 | Mgi Jnum | J:43836 |
| Mgi Id | MGI:1099004 | Doi | 10.1038/ng1197-335 |
| Citation | Caldarone B, et al. (1997) Quantitative trait loci analysis affecting contextual conditioning in mice. Nat Genet 17(3):335-7 |
| abstractText | In an extensive backcross of mice between C3H/HeJ (C3H) and C57BL/6J (B6), we sought to map genes that influence learning and memory as measured by performance in a contextual fear-conditioning paradigm. Our results indicate that there are several genetic regions that have a strong influence on performance in this paradigm. The strongest influences map to the proximal and distal ends of chromosome 1 (lod scores of 5.14 and 4.76, respectively). Other chromosomal regions (chromosomes 3, 7, 8, 9 and 18) were also identified as candidates for regions containing genes influencing contextual fear conditioning, with lod scores ranging from 1.8 to 2.7. |
