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Allele : Lama3<tm1Crt> laminin, alpha 3; targeted mutation 1, William G Carter

Primary Identifier  MGI:2154553 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lama3
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced a genomic fragment containing exon A3. This exon encodes sequences common to both isoforms of the protein. Removal of this exon is predicted to cause a frameshift mutation and result in premature termination of the protein. Immunohistochemistry analysis on skin derived from homozygous mice confirmed that the protein was not detectable.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • alpha3-,
  • alpha3-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele