| Primary Identifier | MGI:2155132 | Allele Type | QTL |
| Gene | Mobq5 | Inheritance Mode | Codominant |
| Strain of Origin | CAST/EiJ | Is Recombinase | false |
| Is Wild Type | false |
| description | This allele is associated with decreased hepatic lipase activity in a codominant manner. |
| molecularNote | This allele confers improved glucose clearance, decreased plasma cholesterol, and resistance to insulin-stimulated glucose uptake compared to C57BL/6J. This allele confers increased food consumption, decreased plasma triglycerides, decreased free fatty acids, and decreased plasma glucose compared to C57BL/6J when animals are placed on a Western diet. In conjunction with Ldlrtm1Her, this allele confers increased food consumption, decreased plasma triglycerides, decreased free fatty acids, and decreased plasma glucose compared to C57BL/6J when animals are placed on a Western diet. |
