Primary Identifier | MGI:2156190 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Ext1 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The gene trap was inserted between exons 1 and 2, resulting in a fusion transcript of exon 1 fused to the gene trap vector sequence. The vector, pGT2TMpfs, contained part of En2, the transmembrane domain of CD4, Beta-geo, IRES, PLAP and pA elements. Northern blot against a cDNA probe for the 3' end of Ext1 showed no 3' mRNA present in mutants. This allele is reported to be a hypomorph (J:92212). |