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Allele : Htt<tm1.1Mfc> huntingtin; targeted mutation 1.1, Marie-Francoise Chesselet
Primary Identifier  MGI:5789600 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Htt
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A fragment extending from 18 bp upstream of the polyglutamine stretch in exon 1 to 100 bp into intron 1 was replaced with human HTT sequence containing 140 CAG repeats. A floxed neo cassette 1.3 kb upstream of exon 1 has been deleted. The repeat number is not stable and may expand or contract.
  • mutations:
  • Insertion
  • synonyms:
  • Htt<Q175neo->,
  • Htt<Q175neo->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

18 Publication categories

Trail: Allele




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