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Publication : A reeler mutant mouse with a new, spontaneous mutation in the reelin gene.

First Author  Andersen TE Year  2002
Journal  Brain Res Mol Brain Res Volume  105
Issue  1-2 Pages  153-6
PubMed ID  12399118 Mgi Jnum  J:79979
Mgi Id  MGI:2429356 Doi  10.1016/s0169-328x(02)00389-3
Citation  Andersen TE, et al. (2002) A reeler mutant mouse with a new, spontaneous mutation in the reelin gene. Brain Res Mol Brain Res 105(1-2):153-6
abstractText  In one of our mouse colonies a reeler-like phenotype appeared spontaneously. The brain histology was identical to the known reeler phenotype. Northern and Western blot analysis and a complementation test showed that the defect is located to the reelin gene. Southern blot and PCR analysis together with information obtained from sequence databases revealed that this defective reelin gene had an approximately 24-kb intragenic deletion comprising exons 13-20.
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