| First Author | Hiai H | Year | 1997 |
| Journal | Leukemia | Volume | 11 Suppl 3 |
| Pages | 193-4 | PubMed ID | 9209340 |
| Mgi Jnum | J:41197 | Mgi Id | MGI:893276 |
| Citation | Hiai H, et al. (1997) To be or not to be a T-lymphomas, that is determined by a dominant gene Tlsm-1 in mouse models. Leukemia 11 Suppl 3:193-4 |
| abstractText | A single dominant gene Tlsm-1 was found to determine the type of spontaneous lymphomas to be T in the cross between AKR/Ms and SL/Kh. Microsatellite analysis mapped Tlsm-1 at the position 61 cM from centromere of Chr. 7. Study of this segment of T-lymphoma prone AKXD Rl strains also showed association of Tlsm-1 with T-lymphomas. On the other hand, lymphoma latency was significantly shorten by a recessive gene lla of SL/Kh. By a quantitative trait analysis, lla was located in class II gene in MHC. |
