| Primary Identifier | MGI:2157016 | Allele Type | Targeted |
| Gene | Lyn | Transmission | Germline |
| Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Insertion of an IRES-neomycin resistance cassette into exon 13 introduced a Tyr508Phe point mutation. Northern blot analysis of bone marrow macrophages detected expression of a truncated message in homozygous mutant mice. Immunoblot analysis detected reduced levels of protein in bone marrow macrophages from homozygous mutant mice. |
