Primary Identifier | MGI:2157331 | Allele Type | Spontaneous |
Gene | Gulo | Inheritance Mode | Recessive |
Strain of Origin | BALB/cBy-Rasa3<scat> | Is Recombinase | false |
Is Wild Type | false |
description | This spontaneous mutation appeared in a BALB/cBy-scat colony at The Jackson Laboratory. The scat and sfx mutations were separated from each other by backcrossing BALB/cBy-scat mice to BALB/cBy mice and observing F2 offspring for those that exhibited the sfx phenotype but not the scat phenotype. |
molecularNote | The mutation in the sfx mouse is a deletion that includes the entire Gulo gene. |