| Primary Identifier | MGI:2157129 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Lyn |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A PGK-neomycin resistance cassette replaced ~11.5kb of sequence, including the promoter and associated regulatory sequences. RT-PCR analysis of liver did not detect wild-type transcript in homozygous mutant mice. Immunoprecipitation and kinase assays of liver and spleen did not detect LYN autokinase activity in homozygous mutant mice. |
