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Allele : Arrb2<tm1Rjl> arrestin, beta 2; targeted mutation 1, Robert J Lefkowitz

Primary Identifier  MGI:2157960 Allele Type  Targeted
Attribute String  Null/knockout Gene  Arrb2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  PGK-neomycin cassette replaced the entire second exon. This resulted in the deletion of amino acids 9-19. The absence of protein was demonstrated by immunoblotting of extracts from brainstem, periaqueductal gray tissue, spleen, lung, and skin.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • betaarr2<->,
  • Arrb2<->,
  • betarr2-KO,
  • Arr3<->,
  • Arrb2<->,
  • Arr3<->,
  • betarr2-KO,
  • betaarr2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

150 Publication categories

Trail: Allele