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Allele : Bdkrb1<tm1Bdr> bradykinin receptor, beta 1; targeted mutation 1, Michael Bader
Primary Identifier  MGI:2158501 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bdkrb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into the coding region of the gene. RNAse protection assays on RNA derived from various tissues of homozygous mice demonstrated that no detectable transcript was produced from this allele. A specific agonist of the encoded receptor failed to elicit responses in isolated ileum from homozygous mice, confirming that no functional protein is produced from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • B1 -,
  • B1-KO,
  • B1 -,
  • B1R<->,
  • B1 receptor-deficient,
  • B1 receptor-deficient,
  • B1R<->,
  • B1-KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

41 Publication categories

Trail: Allele




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