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Allele : Sox9<tm1Crm> SRY (sex determining region Y)-box 9; targeted mutation 1, Benoit de Crombrugghe

Primary Identifier  MGI:2158693 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Sox9
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 300 bp DNA fragment containing part of exon 1 was replaced with an IRES-lacZ gene followed by a neomycin selection cassette. Northern blot and western blot analysis on chondrocytes derived from heterozygous mice demonstrated reduced expression of both the encoded transcript and protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele