|  Help  |  About  |  Contact Us

Allele : Chrm1<tm1Stl> cholinergic receptor, muscarinic 1, CNS; targeted mutation 1, Susumu Tonegawa

Primary Identifier  MGI:2158743 Allele Type  Targeted
Attribute String  Null/knockout Gene  Chrm1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A 3 kb genomic fragment containing the entire coding region of the gene was replaced with a neomycin selection cassette. Northern blot analysis on RNA derived from forebrain of homozygous mice demonstrated that no detectable transcript was produced from this allele. In situ hybridization analysis on sagittal brain sections of homozygous mice further confirmed that the transcript was not expressed.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • M1 -,
  • M1 -
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele