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Allele : Igh-J<tm1Dhu> immunoglobulin heavy chain, joining region; targeted mutation 1, Dennis Huszar
Primary Identifier  MGI:2158307 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igh-J
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
description  Homozygous mutant mice do not develop mature B cells (J:97700).
molecularNote  A ~2.3 kb genomic fragment encompassing the four J-H segments and a flanking D-Q52 segment was replaced with a neomycin selection cassette. Homozygous mice do not produce rearranged immunoglobulin heavy chains.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • JHT,
  • Jh<->,
  • J<H>,
  • JH<0>,
  • JHD,
  • JHD,
  • JHT,
  • J<H>,
  • Jh<->,
  • JH<0>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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