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Allele : St8sia1<tm1Rlp> ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; targeted mutation 1, Richard L Proia

Primary Identifier  MGI:2158360 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  St8sia1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES-lacZ and neomycin selection cassette was inserted into exon 5, which encodes the sialyl S motif, an essential part of the catalytic domain of the encoded protein. TLC analysis on brain extract of homozygous mice demonstrated that no active protein was produced from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • GD3S -,
  • GD3S -,
  • Siat8a<->,
  • Siat8a<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

24 Publication categories

Trail: Allele